منابع مشابه
Serious problems with methotrexate?
Low dose methotrexate (5-25 mg/week) represents a major therapeutic advance in the management of RA in the last decade. Its established efficacy has led to it being used as the lead comparator drug in slow acting anti-rheumatic drug (SAARD) trials, to its increasing use in early disease, and to its inclusion in many drug combinations currently being evaluated. It seems to be the best tolerated ...
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Objective. Limited reported data have reports effects after acute ingestion of methotrexate. Treatment recommendations do not differentiate between exposure routes. Our objective was to determine the frequency of significant toxicity effects and use of therapy after methotrexate ingestion in adults. Methods. We performed a retrospective study on adult cases reported to 6 poison centers over 6 y...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1994
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/33.11.1001